Advances in HIV Mucosal Immunology: Challenges and Opportunities

Florian Hladik from the University of Washington and the Fred Hutchinson Cancer Research Center in Seattle, USA, explains why recent research on how to study the rectal and genital mucosa – featured in the new PLOS Collection Advances in HIV Mucosal Immunology: Challenges and Opportunities – will be key to developing an effective HIV vaccine. Image Credit: Artistic rendition of immune cells and potential HIV targets in the rectal mucosal. Yang, Ochoa, Preza & Anton, 2014 People most often become infected with HIV through sexual transmission; accordingly, their initial exposure to the virus is in their genital or rectal mucosa. …read more

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